I foresee a low scoring game today. Brady has had a few tough games in Buffalo in the past and the Bills defensive speed gives the Pats offense trouble. On the other side, the stingy Patriots defense has had 2 weeks to prepare for J.P Losman  (his last name fits him well) and much better QBs have succumb to Belichick schemes when he has had 2 weeks to prepare. I see a close game through the third quarter with a Losman interception putting a the game away for the Patriots. Final Score Prediction: Patriots 20 Bill 10